Changing rhythms In Parkinson’s disease
Development of motor and non-motor digital progression biomarkers based on continuous, real-life monitoring.
read moreHidden Sorrows of Covid-19 Impact of Stress on Parkinson’s disease Progression
Parkinson’s disease (PD) is caused by progressive loss of nigro-striatal dopamine cells. Converging clinical evidence indicates that PD patients are very sensitive to the effects of psychological stress.
read morePants sign as a predictive marker For postural instability and falling in Parkinson’s disease
Postural instability is one of the clinical hallmarks of Parkinson’s disease (PD).
read moreABCD-Parkinson Developing a bisulfite-sequencing assay
To estimate the concentration of cell-free DNA (cfDNA) in peripheral blood as a surrogate marker of brain cell degeneration.
read moreMicrobiome-mitochondrial interactions Impact neuronal circuits and gut-brain connections in Parkinson’s disease (MIGUT)
Drug treatment with levodopa is the mainstay of treatment, but offers only partial symptomatic relief.
read moreGenetic analyses For MIGUT and JPND projects
Development of novel therapies aimed at slowing disease progression is hampered by the lack of detailed knowledge of the underlying disease mechanisms.
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